Sesaline ® Bio *

The antiradical activity of Sesaline® Bio is evaluated** by measuring the reduction in the cytotoxicity induced by UV-A radiation. Free radicals are generated by the irradiation of fibroblasts in culture with UVA (2.3 J/cm2). Cellular viability is evaluated by an MTT test (a colorimetric method) in the absence of any active principle or in the presence of vitamin E (α -tocopherol) or of Sesaline® Bio.

Without any active principle, toxicity in the fibroblasts is close to 70%, 24 hours after irradiation. The addition of vitamin E or of Sesaline® Bio prior to, during, or after irradiation makes it possible to reduce such cytotoxicity as follows:

When applied prior to irradiation, Sesaline® Bio ** at 50 µg/ml offers the fibroblasts complete protection from the deleterious effects of the UV.

**Test carried out on Sesaline®, an active principle now certified and renamed Sesaline® Bio

Ten female volunteers aged from 29 to 49 years took part in a double-blind, placebo-controlled test in order to evaluate the changes to the mechanical properties of the skin induced by the application of a product (Cutometer). They tested a cream containing 2% Sesaline® Bio and a placebo on the top of the forearm for a period of four weeks**.

In order to preserve all of its qualities, virgin sesame oil is obtained by cold pressing the untoasted seeds.

Apart from the components classically found in the unsaponifiable fraction of vegetable oils, sterols, squalene, and tocopherols, sesame oil contains two powerful natural anti-oxidants, sesamine and sesamoline.

Thanks to a physical process (without the use of solvents), known as molecular distillation, the unsaponifiable fraction of the oil is concentrated so as to obtain the oleodistillate. Sesaline® Bio thus contains between 10 and 15% of unsaponifiable oils, with a minimum of 4% of sesamine, and 2% of sesamoline.