Skinergium is a hydrolysate of the maca root, a plant that is known for its energising and stimulating properties, and which grows on the high plateaux of
Peru. Skinergium is the first-ever extract of the maca plant to be used in cosmetics. It is obtained using a special bio-enzymatic process. lt is recommended for use in skin care formulations to treat mature, tired and dull skin.
(normal human skin fibroblasts)
Skinerqium stimulates qrowth of skin fibroblasts in culture, particularly those that have been aged artificially. At an active ingredient dose of 0.01% administered over
seven days, Skinerium enhanced the growth capability of young fibroblasts by 51%, whilst that of aged fibroblasts increased by 33%.

(19 females double-blind versus placebo, hemifacial area, 8 weeks, 2% active Ingredient)
1. Effect on wrinkles (Silflo resin and video imaging system)
From Week 4. there was a statistically significant difference among the Skinergium group with regard to wrinkle number, mean wrinkle depth and length, and wrinkle surface area. These results were confirmed at Week 8. Conversely, the placebo had no significant effect on these same parameters, either at Week 4 or Week 8.
2. Effect on complexion
(Assessed by a trained evaluator using a nine-point clinical scoring system.) There was a significant improvement in terms of radiance and luminosity from Week 4. After eight weeks, complexion radiance had improved by 35% and luminosity by 25%. Conversely, the placebo had no significant effect on these same parameters, either at Week 4 or Week 8.

CHARACTERISTICS ---------------- Clear, sunset-yellow solution
pH --------------------------------------- 6,0-7,0
DRY EXTRACT (mfm) -------------- 5,0% - 6,5 %
ALPHA AMINE NITROGEN ------- 2,0% - 4,0% on a dry matter basis
TOTAL SUGARS -------------------- 35% -55% on a dry matter basis
SAFETY: The safety 0f skinlrgium has been demonstrated in vitro and tested under dermatological control.
STORAGE: Between 2 and 8° C, in its original container and away from light.
SKINERGIUM is strictly designed for cosmetic applications (topical route).